According to the results of a new large-scale review, supplementation with folic acid have no effect on the risk of cancer in humans.As researchers have found, short-term use of such additives, most likely, will not increase or reduce the overall risk of developing cancer, and has very little effect on the probability of occurrence of certain cancers such as colon, prostate, lung and breast cancer.The study was published January 24 online version of the journal The Lancet.
«This study helps to ensure the safety of folic acid intake for a period not exceeding five years - in the form of supplements as well as in the form of fortified foods," - said in a journal news release on behalf of the author of the study, Robert Clark,Oxford University employee.
«Food fortification nationwide involves the use of much lower doses of folic acid than the doses studied in the study, which is reassuring not only for the United States, which since 1998 is enriched with folic acid flour to prevent neural tube defects (su
researchers analyzed the results of all the end of 2010 randomized studies that have been devoted to the study of supplementation with folic acid and other B vitamins or without them.The analysis, therefore, data is captured about 50 thousand people.
Those who take folic acid every day for a period of 5 years, there was no likelihood of developing cancer is much more than those who took placebo pills, the study found.The researchers found that the cancer developed in 7.7% of those who took folic acid, whereas in the placebo group, the disease was diagnosed in 7.3% of men.
Even among those who took the highest average daily doses of folic acid, the risk of cancer did not increase as the researchers note.They also found no evidence that the risk of cancer increases folic acid for longer periods of time.
«This meta-analysis did not confirm nor the opportunity to express the method of cancer prevention or fears of a sharp increase in the risk of cancer due to intake of folic acid supplements," - said Clark."It remains to be found, there will be shown, ultimately, any beneficial or deleterious effects on the incidence of malignant neoplasms at an even longer period of observation or treatment."
The accompanying comments Cornelia Ulrich, director of the National Center for Tumor Diseases and the German Cancer Research Center, and Joshua Miller, a fellow at Rutgers University, said that it is important to note that folate is able to protect against the development of cancer and cause the growth of existing cancercells.