scientific team, which includes experts from different countries, announced the creation of a technique to identify patients who do not need prescription drugs to suppress the immune system after a kidney transplant.The new technique was able to successfully pass the tests with the participation of several dozen people, each of whom had refused to receive immunosuppressive drugs after the transplant donor organ for various reasons.
His work began with the study authors find patients izbegnuvshih rejection of the transplanted organ, despite the discontinuation of medication to suppress the immune system.As a result of seven years of research conducted in medical institutions of Great Britain, Canada, Germany, Belgium and many other countries around the world, experts managed to find a total of 36 of these patients, the vast majority of whom were forced to interrupt a course of immunosuppressive drugs or because of adverse reactions, oralso because of the associated serious diseases.As noted above, all of
reports on the pages an Internet resource medportal.ru, results of a series of laboratory studies have shown that all of these patients had a number of immunological and genetic features, among which are the increased activity of a group of genes responsible for regulating reproduction and specialization B-lymphocytes.
Based on the information received, the authors were able to develop a set of analysis, which provides the possibility of determining the likelihood that a patient will not need prescriptions to suppress the immune system after transplantation of internal organs.The high accuracy of the proposed method was successfully confirmed by the results of a control experiment conducted with a group of patients with a donor kidney, among which there were 24 people who do not require such preparations.
In this regard, it is worth noting another recent study, which focused on the immunological characteristics of patients with a lower risk of rejection of donor kidneys.The authors of this research also concluded that such a feature of patients due to the genes responsible for the regulation of the activity of B-lymphocytes.
Detailed reports on the results of both of these papers are published in the journal «The Journal of Clinical Investigation».