severity and duration of acute or persistent diarrhea in children can be reduced by the use of drugs in the treatment of zinc, according Solvay-pharma.ru.But scientists consider it necessary to continue the begun their studies in order to determine the exact nature of Bole antidiarrheal action of this chemical element.
Dr. Marek Lukasik (Marek Lukacik, Medical College of Georgia, Augusta) and his colleagues conducted a meta-analysis on 22 relevant studies.Some of these studies also included 16 studies that evaluated the positive input of the effects due to intake of zinc from 15,231 children with acute diarrhea, and 6 studies that swept 2968 children with persistent diarrhea.
As the researchers note, in all these cases, the use of zinc led to a decrease in the average duration of both acute and persistent diarrhea.In addition, the use of zinc supplementation causes a decrease in the average stool frequency by 18.8% in children with acute diarrhea and 12.5% in children with persistent diarrhea.
results of the study also suggest that the use of zinc supplements is preventive in nature.Their use resulted in reduction of the probability of both types of diarrhea by about 18% compared to placebo.
However, the results of most studies show that zinc supplements are more likely than placebo to cause vomiting.If we consider this aspect, there is zinc gluconate had more severe side effects than sulfate or zinc acetate.
Summing up, the authors, based on the results, which are consistent with a large number of previously published clinical data, and previous meta-analyzes and systematic reviews, are confident that therapy with zinc is useful in the treatment and prevention of acute andpersistent diarrhea.