Maternal stem cells migrated to the fetus during pregnancy, can take over the function of pancreatic cells that produce insulin.To such conclusions the American and British researchers from studying the genome of blood cells and the pancreas of children with diabetes of the first type.
known that in some cases the fetus from the mother can receive a number of stem cells that remain in the body for years child without causing rejection by the immune system.This phenomenon, the consequences of which health is still not fully understood, is called "microchimerism."
The study, conducted by experts of the University of Bristol and the Centre for Cancer Research in Seattle, scientists have identified a high content of DNA in the maternal blood tests 20% of children and adults with diabetes first type.
Initially, the researchers found the presence of foreign cells a consequence of the pathological process, which somehow could be associated with the development of severe disease.However, they failed to find a
As a result, scientists have concluded that the mother's cells are not only harmful to the child, but may even participate in the partial restoration responsible for insulin production of the pancreas islet formation in the development of diabetes.
In addition, the ability of cells mother for such a long time to stay in the body of the child says that, at least in some cases, the mother may be an ideal donor pancreatic islet cells for patients with diabetes.
It is possible that the tolerance to the parent cell due to the fact that they fall into the child's body when the immune system is not developed enough to recognize and destroy them as foreign, the authors of a study published in the latest issue of the journal Proceedings of the National Academy ofSciences.